3PVD
Crystal structure of P domain dimer of Norovirus VA207 complexed with 3'-sialyl-Lewis x tetrasaccharide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Capsid | polymer | 316 | 34674.7 | 2 | UniProt (Q91H09) Pfam (PF08435) | Human calicivirus | |
| 2 | C, D (C, D) | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose | branched | 820.7 | 2 | In PDB BIRD (PRD_900122) GlyTouCan (G07675NG) | Sialyl-Lewis X antigen, alpha anomer | ||
| 3 | E, F (A, B) | water | water | 18.0 | 347 | Chemie (HOH) |
Sequence modifications
A, B: 222 - 537 (UniProt: Q91H09)
| PDB | External Database | Details |
|---|---|---|
| Asn 289 | Thr 289 | engineered mutation |
| Asp 374 | Asn 374 | engineered mutation |
| Gly 425 | Arg 425 | engineered mutation |
| Arg 466 | Gln 466 | engineered mutation |
| Ala 482 | Val 482 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69349.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1641.5 | |
| All* | Total formula weight | 70990.8 |
