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3PRY

Crystal structure of the middle domain of human HSP90-beta refined at 2.3 A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Heat shock protein HSP 90-betapolymer26831831.33UniProt (P08238)
Pfam (PF00183)
Homo sapiens (human)HSP 90, Heat shock 84 kDa, HSP 84, HSP84
2D, E
(A, B)
SULFATE IONnon-polymer96.12Chemie (SO4)
3F
(B)
GLYCEROLnon-polymer92.11Chemie (GOL)
4G, H, I, J, K
(B, C)
1,2-ETHANEDIOLnon-polymer62.15Chemie (EDO)
5L, M, N
(A, B, C)
waterwater18.0220Chemie (HOH)
Sequence modifications
A, B, C: 284 - 543 (UniProt: P08238)
PDBExternal DatabaseDetails
Met 283-initiating methionine
Ala 544-expression tag
Glu 545-expression tag
Asn 546-expression tag
Leu 547-expression tag
Tyr 548-expression tag
Phe 549-expression tag
Gln 550-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight95493.9
Non-Polymers*Number of molecules8
Total formula weight594.6
All*Total formula weight96088.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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