3PR3

Crystal structure of Plasmodium falciparum glucose-6-phosphate isomerase (PF14_0341) in complex with fructose-6-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glucose-6-phosphate isomerase	polymer	597	69655.8	2	UniProt (Q8ILA4) Pfam (PF00342)	Plasmodium falciparum
2	C, E (A, B)	6-O-phosphono-beta-D-fructofuranose	non-polymer		260.1	2	Chemie (F6P)
3	D, F (A, B)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
4	G, H (A, B)	water	water		18.0	791	Chemie (HOH)

Sequence modifications

A, B: 1 - 579 (UniProt: Q8ILA4)

PDB	External Database	Details
Met -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Arg -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	139311.6
Non-Polymers*	Number of molecules	4
	Total formula weight	710.2
All*	Total formula weight	140021.8

*Water molecules are not included.