3PQ1

Crystal structure of human mitochondrial poly(A) polymerase (PAPD1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Poly(A) RNA polymerase	polymer	464	52330.4	2	UniProt (Q9NVV4) Pfam (PF17797) Pfam (PF22600) Pfam (PF03828)	Homo sapiens (human)	PAP, PAP-associated domain-containing protein 1, Polynucleotide adenylyltransferase, Terminal uridylyltransferase 1, TUTase 1, mtPAP

Sequence modifications

A, B: 44 - 134 (UniProt: Q9NVV4)

PDB	External Database	Details
Mse 23	-	expression tag
Gly 24	-	expression tag
Ser 25	-	expression tag
Ser 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
Ser 33	-	expression tag
Ser 34	-	expression tag
Gly 35	-	expression tag
Leu 36	-	expression tag
Val 37	-	expression tag
Pro 38	-	expression tag
Arg 39	-	expression tag
Gly 40	-	expression tag
Ser 41	-	expression tag
His 42	-	expression tag
Mse 43	-	expression tag

A, B: 172 - 452 (UniProt: Q9NVV4)

PDB	External Database	Details
Unk 151	-	SEE REMARK 999
Unk 152	-	SEE REMARK 999
Unk 153	-	SEE REMARK 999
Unk 154	-	SEE REMARK 999
Unk 155	-	SEE REMARK 999
Unk 156	-	SEE REMARK 999
Unk 157	-	SEE REMARK 999
Ala 325	Asp 325	engineered mutation

A, B: 490 - 538 (UniProt: Q9NVV4)

PDB	External Database	Details
Unk 464	-	SEE REMARK 999
Unk 465	-	SEE REMARK 999
Unk 466	-	SEE REMARK 999
Unk 467	-	SEE REMARK 999
Unk 468	-	SEE REMARK 999
Unk 469	-	SEE REMARK 999
Unk 470	-	SEE REMARK 999
Unk 471	-	SEE REMARK 999
Unk 472	-	SEE REMARK 999
Unk 473	-	SEE REMARK 999
Unk 474	-	SEE REMARK 999
Unk 475	-	SEE REMARK 999
Unk 476	-	SEE REMARK 999
Unk 477	-	SEE REMARK 999
Unk 478	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	104660.8
All*	Total formula weight	104660.8

*Water molecules are not included.