3PP4
Epitope characterization and crystal structure of GA101 provide insights into the molecular basis for the type I / type II distinction of anti- CD20 antibodies
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | GA101 Fab heavy chain | polymer | 224 | 23969.9 | 1 | Mus musculus (mouse) | ||
| 2 | B (L) | GA101 Fab light chain | polymer | 219 | 23964.8 | 1 | Mus musculus (mouse) | ||
| 3 | C (P) | B-lymphocyte antigen CD20 | polymer | 25 | 2852.1 | 1 | UniProt (P11836) | Homo sapiens | B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1 |
| 4 | D (H) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E, F, G (H, L, P) | water | water | 18.0 | 759 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50786.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 50822.2 |
