3PHC
Crystal Structure of Plasmodium falciparum purine nucleoside phosphorylase in complex with DADMe-ImmG
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... (A, B, C, D, E...) | Purine nucleoside phosphorylase | polymer | 275 | 30431.0 | 6 | UniProt (Q8T9Z7) Pfam (PF01048) UniProt (by SIFTS) (Q8I3X4) | Plasmodium falciparum | |
2 | G, L, Q (A, C, E) | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) | |||
3 | H, J, M, O, R... (A, B, C, D, E...) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
4 | I, K, N, P, S... (A, B, C, D, E...) | 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one | non-polymer | 279.3 | 6 | Chemie (IM5) | |||
5 | AA, V, W, X, Y... (F, A, B, C, D...) | water | water | 18.0 | 312 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 0 - 245 (UniProt: Q8T9Z7)
PDB | External Database | Details |
---|---|---|
Leu 1 | - | expression tag |
Lys 246 | - | expression tag |
Gly 247 | - | expression tag |
Glu 248 | - | expression tag |
Phe 249 | - | expression tag |
Glu 250 | - | expression tag |
Ala 251 | - | expression tag |
Tyr 252 | - | expression tag |
Val 253 | - | expression tag |
Glu 254 | - | expression tag |
Gln 255 | - | expression tag |
Lys 256 | - | expression tag |
Leu 257 | - | expression tag |
Ile 258 | - | expression tag |
Ser 259 | - | expression tag |
Glu 260 | - | expression tag |
Glu 261 | - | expression tag |
Asp 262 | - | expression tag |
Leu 263 | - | expression tag |
Asn 264 | - | expression tag |
Ser 265 | - | expression tag |
Ala 266 | - | expression tag |
Val 267 | - | expression tag |
Asp 268 | - | expression tag |
His 269 | - | expression tag |
His 270 | - | expression tag |
His 271 | - | expression tag |
His 272 | - | expression tag |
His 273 | - | expression tag |
His 274 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 182585.8 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 2362.9 | |
All* | Total formula weight | 184948.7 |