3PEH
Crystal Structure of the N-terminal domain of an HSP90 from Plasmodium Falciparum, PFL1070c in the presence of a thienopyrimidine derivative
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Endoplasmin homolog | polymer | 281 | 32065.3 | 2 | UniProt (Q8I0V4) Pfam (PF13589) In PDB | Plasmodium falciparum 3D7 | |
2 | A, B | 2-amino-4-{2,4-dichloro-5-[2-(diethylamino)ethoxy]phenyl}-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide | non-polymer | 482.4 | 2 | Chemie (IBD) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) |
Sequence modifications
A, B: 68 - 330 (UniProt: Q8I0V4)
PDB | External Database | Details |
---|---|---|
Met 50 | - | expression tag |
His 51 | - | expression tag |
His 52 | - | expression tag |
His 53 | - | expression tag |
His 54 | - | expression tag |
His 55 | - | expression tag |
His 56 | - | expression tag |
Ser 57 | - | expression tag |
Ser 58 | - | expression tag |
Gly 59 | - | expression tag |
Arg 60 | - | expression tag |
Glu 61 | - | expression tag |
Asn 62 | - | expression tag |
Leu 63 | - | expression tag |
Tyr 64 | - | expression tag |
Phe 65 | - | expression tag |
Gln 66 | - | expression tag |
Gly 67 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 64130.6 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1157.0 | |
All* | Total formula weight | 65287.6 |