3PEF
Crystal structure of gamma-hydroxybutyrate dehydrogenase from Geobacter metallireducens in complex with NADP+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | 6-phosphogluconate dehydrogenase, NAD-binding | polymer | 287 | 29924.7 | 8 | UniProt (Q39R98) Pfam (PF03446) Pfam (PF14833) | Geobacter metallireducens | |
| 2 | BA, I, O, Q, S... (H, A, B, C, D...) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 8 | Chemie (NAP) PubChem (5885) PubChem (46936685) PubChem (4412) PubChem (90473931) PubChem (91972139) PubChem (145946263) PubChem (153311489) PubChem (174001641) PubChem (71717786) PubChem (165382010) | |||
| 3 | J, K, L, P, R... (A, B, C, E) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) PubChem (753) | |||
| 4 | AA, CA, M, T, X (G, H, A, D, E) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) PubChem (8117) | |||
| 5 | N (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | DA, EA, FA, GA, HA... (A, B, C, D, E...) | water | water | 18.0 | 999 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 287 (UniProt: Q39R98)
| PDB | External Database | Details |
|---|---|---|
| Ser 1 | Met 1 | engineered mutation |
| Tyr 285 | Ile 285 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 239397.8 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 7184.6 | |
| All* | Total formula weight | 246582.3 |
