3PDN
Crystal structure of SmyD3 in complex with methyltransferase inhibitor sinefungin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SET and MYND domain-containing protein 3 | polymer | 428 | 49178.1 | 1 | UniProt (Q9H7B4) Pfam (PF00856) Pfam (PF01753) | Homo sapiens (human) | Zinc finger MYND domain-containing protein 1 |
| 2 | B (A) | SINEFUNGIN | non-polymer | 381.4 | 1 | Chemie (SFG) | |||
| 3 | C, D, E, F, G... (A) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 4 | I, J, K (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 5 | L, M (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | N (A) | water | water | 18.0 | 645 | Chemie (HOH) |
Sequence modifications
A: 1 - 428 (UniProt: Q9H7B4)
| PDB | External Database | Details |
|---|---|---|
| Asn 13 | Lys 13 | SEE REMARK 999 |
| Arg 140 | Lys 140 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49178.1 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1178.8 | |
| All* | Total formula weight | 50356.9 |
