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3PCV

Crystal structure analysis of human leukotriene C4 synthase at 1.9 angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Leukotriene C4 synthasepolymer15617411.51UniProt (Q16873)
Pfam (PF01124)
Homo sapiens (human)LTC4 synthase, Leukotriene-C(4) synthase
2B
(A)
GLUTATHIONEnon-polymer307.31Chemie (GSH)
3C, D, E, F, G...
(A)
DODECYL-BETA-D-MALTOSIDEnon-polymer510.611Chemie (LMT)
4N, O, P, Q
(A)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
5R, S, T, U
(A)
UNKNOWN LIGANDnon-polymer4Chemie (UNL)
6V, W
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
7X
(A)
waterwater18.094Chemie (HOH)
Sequence modifications
A: 1 - 150 (UniProt: Q16873)
PDBExternal DatabaseDetails
His 151-expression tag
His 152-expression tag
His 153-expression tag
His 154-expression tag
His 155-expression tag
His 156-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight17411.5
Non-Polymers*Number of molecules22
Total formula weight6364.5
All*Total formula weight23776.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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