3P95
Human mesotrypsin complexed with bovine pancreatic trypsin inhibitor variant (BPTI-K15R/R17D)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PRSS3 protein | polymer | 224 | 24257.5 | 1 | UniProt (Q8N2U3) Pfam (PF00089) UniProt (by SIFTS) (P35030) | Homo sapiens (human) | |
| 2 | B (E) | Pancreatic trypsin inhibitor | polymer | 58 | 6513.5 | 1 | UniProt (P00974) Pfam (PF00014) | Bos taurus (bovine cow domestic cattle domestic cow) | Aprotinin, Basic protease inhibitor, BPI, BPTI |
| 3 | C (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 4 | D, E (A, E) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence modifications
A: 16 - 246 (UniProt: Q8N2U3)
E: 1 - 58 (UniProt: P00974)
| PDB | External Database | Details |
|---|---|---|
| Ala 195 | Ser 204 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Arg 15 | Lys 50 | engineered mutation |
| Asp 17 | Arg 52 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30770.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 30811.0 |
