3P86

Crystal structure of CTR1 kinase domain mutant D676N in complex with staurosporine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Serine/threonine-protein kinase CTR1	polymer	309	35218.5	2	UniProt (Q05609) Pfam (PF07714)	Arabidopsis thaliana (mouse-ear cress thale-cress)
2	C (A)	STAUROSPORINE	non-polymer		466.5	1	Chemie (STU)
3	D, E (A, B)	water	water		18.0	61	Chemie (HOH)

Sequence modifications

A, B: 540 - 821 (UniProt: Q05609)

PDB	External Database	Details
Met 513	-	expression tag
Lys 514	-	expression tag
His 515	-	expression tag
His 516	-	expression tag
His 517	-	expression tag
His 518	-	expression tag
His 519	-	expression tag
His 520	-	expression tag
Pro 521	-	expression tag
Met 522	-	expression tag
Ser 523	-	expression tag
Asp 524	-	expression tag
Tyr 525	-	expression tag
Asp 526	-	expression tag
Ile 527	-	expression tag
Pro 528	-	expression tag
Thr 529	-	expression tag
Thr 530	-	expression tag
Glu 531	-	expression tag
Asn 532	-	expression tag
Leu 533	-	expression tag
Tyr 534	-	expression tag
Phe 535	-	expression tag
Gln 536	-	expression tag
Gly 537	-	expression tag
Ala 538	-	expression tag
Met 539	-	expression tag
Asn 676	Asp 676	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70436.9
Non-Polymers*	Number of molecules	1
	Total formula weight	466.5
All*	Total formula weight	70903.5

*Water molecules are not included.