3P7G

Structure of the human Langerin carbohydrate recognition domain in complex with mannose

Replaces:  3BC7

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	C-type lectin domain family 4 member K	polymer	146	16852.6	4	UniProt (Q9UJ71) Pfam (PF00059)	Homo sapiens (human)	Langerin
2	E, G, I, K (A, B, C, D)	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
3	F, H, J, L (A, B, C, D)	alpha-D-mannopyranose	non-polymer		180.2	4	Chemie (MAN)
4	M, N, O, P (A, B, C, D)	water	water		18.0	593	Chemie (HOH)

Sequence modifications

A, B, C, D: 193 - 328 (UniProt: Q9UJ71)

PDB	External Database	Details
Ser 329	-	expression tag
Ala 330	-	expression tag
Trp 331	-	expression tag
Ser 332	-	expression tag
His 333	-	expression tag
Pro 334	-	expression tag
Gln 335	-	expression tag
Phe 336	-	expression tag
Glu 337	-	expression tag
Lys 338	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	67410.5
Non-Polymers*	Number of molecules	8
	Total formula weight	880.9
All*	Total formula weight	68291.5

*Water molecules are not included.