3P7A

p38 inhibitor-bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Mitogen-activated protein kinase 14	polymer	366	42100.0	1	UniProt (P47811) Pfam (PF00069) In PDB	Mus musculus (mouse)	MAP kinase 14, MAPK 14, CRK1, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha
2	A	octyl beta-D-glucopyranoside	non-polymer		292.4	1	Chemie (BOG)
3	A	1-[5-tert-butyl-2-(1,1-dioxidothiomorpholin-4-yl)thiophen-3-yl]-3-naphthalen-1-ylurea	non-polymer		457.6	1	Chemie (P7A)
4		water	water		18.0	32	Chemie (HOH)

Sequence modifications

A: 2 - 360 (UniProt: P47811)

PDB	External Database	Details
Met -5	-	expression tag
Ala -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42100.0
Non-Polymers*	Number of molecules	2
	Total formula weight	750.0
All*	Total formula weight	42849.9

*Water molecules are not included.