3P5S
Structural insights into the catalytic mechanism of CD38: Evidence for a conformationally flexible covalent enzyme-substrate complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | CD38 molecule | polymer | 278 | 31587.1 | 2 | UniProt (Q9TTF5) Pfam (PF02267) In PDB | Bos taurus (bovine cow domestic cattle domestic cow) | Ecto-NAD+ glycohydrolase |
2 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | A, B | [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3R,4R)-4-fluoro-3-hydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate | non-polymer | 545.3 | 2 | Chemie (AVU) | |||
5 | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 63174.3 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1725.2 | |
All* | Total formula weight | 64899.4 |