3P5K
P38 inhibitor-bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 14 | polymer | 366 | 42100.0 | 1 | UniProt (P47811) Pfam (PF00069) | Mus musculus (mouse) | MAP kinase 14, MAPK 14, CRK1, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha |
| 2 | B (A) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 1 | Chemie (BOG) | |||
| 3 | C (A) | 1-{5-tert-butyl-3-[(1,1-dioxidothiomorpholin-4-yl)carbonyl]thiophen-2-yl}-3-naphthalen-1-ylurea | non-polymer | 485.6 | 1 | Chemie (P5K) | |||
| 4 | D (A) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A: 2 - 360 (UniProt: P47811)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | expression tag |
| Ala -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| His 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42100.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 778.0 | |
| All* | Total formula weight | 42878.0 |
