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3P5B

The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1PProprotein convertase subtilisin/kexin type 9polymer9210490.11UniProt (Q8NBP7)
Pfam (PF05922)
In PDB
Homo sapiens (human)Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9
2AProprotein convertase subtilisin/kexin type 9polymer54057371.71UniProt (Q8NBP7)
Pfam (PF00082)
Pfam (PF18459)
Pfam (PF18464)
Pfam (PF18463)
In PDB
Homo sapiens (human)Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9
3LLow density lipoprotein receptor variantpolymer40044762.51UniProt (Q59FQ1)
Pfam (PF14670)
Pfam (PF00058)
UniProt (by SIFTS) (P01130)
In PDB
Homo sapiens (human)
4A, LCALCIUM IONnon-polymer40.13Chemie (CA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight112624.3
Non-Polymers*Number of molecules3
Total formula weight120.2
All*Total formula weight112744.5
*Water molecules are not included.

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PDB entries from 2024-04-24

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