3P5B
The structure of the LDLR/PCSK9 complex reveals the receptor in an extended conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (P) | Proprotein convertase subtilisin/kexin type 9 | polymer | 92 | 10490.1 | 1 | UniProt (Q8NBP7) Pfam (PF05922) | Homo sapiens (human) | Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9 |
| 2 | B (A) | Proprotein convertase subtilisin/kexin type 9 | polymer | 540 | 57371.7 | 1 | UniProt (Q8NBP7) Pfam (PF00082) Pfam (PF18459) Pfam (PF18464) Pfam (PF18463) | Homo sapiens (human) | Neural apoptosis-regulated convertase 1, NARC-1, Proprotein convertase 9, PC9, Subtilisin/kexin-like protease PC9 |
| 3 | C (L) | Low density lipoprotein receptor variant | polymer | 400 | 44762.5 | 1 | UniProt (Q59FQ1) Pfam (PF14670) Pfam (PF00058) UniProt (by SIFTS) (P01130) | Homo sapiens (human) | |
| 4 | D, E, F (A, L) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 112624.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 120.2 | |
| All* | Total formula weight | 112744.5 |
