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3P3P

Factor inhibiting HIF-1 Alpha in complex with Notch 1 fragment mouse notch (1997-2016) peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hypoxia-inducible factor 1-alpha inhibitorpolymer34940328.31UniProt (Q9NWT6)
Pfam (PF13621)
Homo sapiens (human)Hypoxia-inducible factor asparagine hydroxylase, Factor inhibiting HIF-1, FIH-1
2B
(B)
Notch 1 proteinpolymer181929.01UniProt (Q8K428)
UniProt (by SIFTS) (Q01705)
Mus musculus
3C
(A)
FE (II) IONnon-polymer55.81Chemie (FE2)
4D
(A)
2-OXOGLUTARIC ACIDnon-polymer146.11Chemie (AKG)
5E, F
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
6G, H, I
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
7J, K
(A, B)
waterwater18.0163Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42257.3
Non-Polymers*Number of molecules7
Total formula weight670.4
All*Total formula weight42927.7
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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