3P1R
Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26562.9 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Stratifin, Epithelial cell marker protein 1 |
| 2 | B (P) | 6-mer peptide from Potassium channel subfamily K member 9 | polymer | 6 | 857.0 | 1 | UniProt (Q9NPC2) | TASK-3 peptide | |
| 3 | C, D, E, K (A) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | F, G, H, I (A) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | J (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | L, M (A, P) | water | water | 18.0 | 366 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Val 38 | Cys 38 | engineered mutation |
| His 166 | Asn 166 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27419.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 279.1 | |
| All* | Total formula weight | 27699.0 |
