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3P1O

Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilisator Fusicoccin A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
14-3-3 protein sigmapolymer23526501.91UniProt (P31947)
Pfam (PF00244)
Homo sapiens (human)Stratifin, Epithelial cell marker protein 1
2B
(P)
6-mer peptide from Potassium channel subfamily K member 9polymer6857.01UniProt (Q9NPC2)HOMO SAPIENSTASK-3 peptide
3C
(A)
FUSICOCCINnon-polymer680.81Chemie (FSC)
4D
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5E
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
6F, G, H, I
(A)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
7J, K
(A, P)
waterwater18.0205Chemie (HOH)
Sequence modifications
A: 1 - 231 (UniProt: P31947)
PDBExternal DatabaseDetails
Ala -3-expression tag
Met -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight27358.8
Non-Polymers*Number of molecules7
Total formula weight853.6
All*Total formula weight28212.4
*Water molecules are not included.

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PDB entries from 2024-11-06

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