3P1D
Crystal structure of the bromodomain of human CREBBP in complex with N-Methyl-2-pyrrolidone (NMP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | CREB-binding protein | polymer | 119 | 14223.3 | 2 | UniProt (Q92793) Pfam (PF00439) In PDB | Homo sapiens (human) | |
| 2 | A | THIOCYANATE ION | non-polymer | 58.1 | 1 | Chemie (SCN) | |||
| 3 | A, B | 1-methylpyrrolidin-2-one | non-polymer | 99.1 | 2 | Chemie (MB3) | |||
| 4 | B | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 5 | water | water | 18.0 | 158 | Chemie (HOH) |
Sequence modifications
A, B: 1081 - 1197 (UniProt: Q92793)
| PDB | External Database | Details |
|---|---|---|
| Ser 1079 | - | expression tag |
| Met 1080 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28446.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 295.4 | |
| All* | Total formula weight | 28742.1 |
