3OZK
Crystal structure of human transthyretin variant A25T in complex with thyroxine (T4)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 127 | 13807.4 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (human) | Prealbumin, TBPA, TTR, ATTR |
| 2 | C, D (A, B) | 3,5,3',5'-TETRAIODO-L-THYRONINE | non-polymer | 776.9 | 2 | Chemie (T44) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Thr 25 | Ala 45 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27614.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1553.7 | |
| All* | Total formula weight | 29168.5 |
