3OZG
Crystal Structure of Plasmodium falciparum Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase in complex with S-SerMe-ImmH phosphonate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | polymer | 250 | 28410.7 | 4 | UniProt (P20035) Pfam (PF00156) In PDB | Plasmodium falciparum FCR-3/Gambia | HGXPRTase, HGXPRT, HGPRT |
2 | A, B, C, D | [(3S)-4-hydroxy-3-{[(4-oxo-4,5-dihydro-3H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino}butyl]phosphonic acid | non-polymer | 316.3 | 4 | Chemie (SSI) | |||
3 | A, B, C, D | PYROPHOSPHATE 2- | non-polymer | 176.0 | 4 | Chemie (POP) | |||
4 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
5 | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 231 (UniProt: P20035)
PDB | External Database | Details |
---|---|---|
Met -18 | - | expression tag |
Gly -17 | - | expression tag |
Gly -16 | - | expression tag |
Ser -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
Gly -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 113642.8 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 2066.1 | |
All* | Total formula weight | 115708.8 |