3OYK
Crystal structure of the PFV S217H mutant intasome bound to manganese
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | PFV integrase | polymer | 395 | 44507.8 | 2 | UniProt (P14350) Pfam (PF17921) Pfam (PF00665) Pfam (PF18103) In PDB | Human spumaretrovirus (SFVcpz(hu)) | p42In |
2 | C | DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3') | polymer | 19 | 5834.8 | 1 | |||
3 | D | DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3') | polymer | 17 | 5195.4 | 1 | |||
4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | A, B | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
6 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
7 | A, B | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
8 | A | AMMONIUM ION | non-polymer | 18.0 | 1 | Chemie (NH4) | |||
9 | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 392 (UniProt: P14350)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Pro -1 | - | expression tag |
Gly 0 | - | expression tag |
His 217 | Gly 968 | engineered mutation |
Gly 218 | Ser 969 | variant |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 100045.7 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 753.8 | |
All* | Total formula weight | 100799.5 |