3OY6
The crystal structure of uPA complex with peptide inhibitor MH036 at pH4.6
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | U | Urokinase-type plasminogen activator | polymer | 253 | 28442.4 | 1 | UniProt (P00749) Pfam (PF00089) In PDB | Homo sapiens (human) | U-plasminogen activator, uPA, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A, Urokinase-type plasminogen activator chain B |
2 | P | MH036 | polymer | 23 | 2340.6 | 1 | |||
3 | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
U: 16 - 250 (UniProt: P00749)
PDB | External Database | Details |
---|---|---|
Ala 122 | Cys 299 | engineered mutation |
Gln 145 | Asn 322 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 30783.0 | |
All* | Total formula weight | 30783.0 |