3OVE
Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Growth factor receptor-bound protein 2 | polymer | 117 | 13614.3 | 1 | UniProt (P62993) Pfam (PF00017) | Homo sapiens (human) | Adapter protein GRB2, Protein Ash, SH2/SH3 adapter GRB2 |
| 2 | B (B) | PYAC7CN | polymer | 5 | 553.5 | 1 | |||
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D (A) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
A: 53 - 163 (UniProt: P62993)
| PDB | External Database | Details |
|---|---|---|
| Asn 164 | - | expression tag |
| Asn 165 | - | expression tag |
| Asn 166 | - | expression tag |
| Asn 167 | - | expression tag |
| Asn 168 | - | expression tag |
| Asn 169 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 14167.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 14203.2 |






