3OV6

CD1c in complex with MPM (mannosyl-beta1-phosphomycoketide)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Beta-2-microglobulin, T-cell surface glycoprotein CD1c, T-cell surface glycoprotein CD1b	polymer	397	44512.4	1	UniProt (P61769) UniProt (P29017) UniProt (P29016) Pfam (PF07654) Pfam (PF16497)	Homo sapiens (human)	Beta-2-microglobulin form pI 5.3
2	B (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
3	C (A)	DODECANE	non-polymer		170.3	1	Chemie (D12)
4	D (A)	1-O-[(S)-hydroxy{[(4S,8S,16S,20S)-4,8,12,16,20-pentamethylheptacosyl]oxy}phosphoryl]-beta-D-mannopyranose	non-polymer		709.0	1	Chemie (MK0)
5	E (A)	water	water		18.0	38	Chemie (HOH)

Sequence modifications

A: 1001 - 1099 (UniProt: P61769)

PDB	External Database	Details
Ala 998	-	expression tag
Asp 999	-	expression tag
Pro 1000	-	expression tag
Gly 1100	-	linker
Gly 1101	-	linker
Gly 1102	-	linker
Gly 1103	-	linker
Ser 1104	-	linker
Gly 1105	-	linker
Gly 1106	-	linker
Ser 1107	-	linker
Gly 1108	-	linker
Ser 1109	-	linker
Gly 1110	-	linker
Gly 1111	-	linker
Gly 1112	-	linker
Ser 1113	-	linker
Ser 1114	-	linker

A: 1 - 183 (UniProt: P29017)

PDB	External Database	Details
Gln 52	Asn 70	engineered mutation
Gln 57	Asn 75	engineered mutation
Gly 108	Lys 126	engineered mutation
Gln 128	Asn 146	engineered mutation

A: 184 - 278 (UniProt: P29016)

PDB	External Database	Details
Gln 241	Asn 258	engineered mutation
Gly 242	Trp 259	engineered mutation
His 279	-	expression tag
His 280	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44512.4
Non-Polymers*	Number of molecules	3
	Total formula weight	1100.5
All*	Total formula weight	45613.0

*Water molecules are not included.