3OSA
Estrogen Receptor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Estrogen receptor | polymer | 258 | 29465.6 | 4 | UniProt (P03372) Pfam (PF00104) In PDB | Homo sapiens (human) | ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
2 | A, B, C, D | 4-[1-(3-methylbut-2-en-1-yl)-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol | non-polymer | 362.3 | 4 | Chemie (KN3) | |||
3 | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 299 - 553 (UniProt: P03372)
PDB | External Database | Details |
---|---|---|
Ser 296 | - | expression tag |
Asn 297 | - | expression tag |
Ala 298 | - | expression tag |
Arg 372 | Leu 372 | engineered mutation |
Ser 536 | Leu 536 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 117862.4 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1449.4 | |
All* | Total formula weight | 119311.8 |