3OSA
Estrogen Receptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Estrogen receptor | polymer | 258 | 29465.6 | 4 | UniProt (P03372) Pfam (PF00104) | Homo sapiens (human) | ER, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1 |
| 2 | E, F, G, H (A, B, C, D) | 4-[1-(3-methylbut-2-en-1-yl)-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol | non-polymer | 362.3 | 4 | Chemie (KN3) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 299 - 553 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Ser 296 | - | expression tag |
| Asn 297 | - | expression tag |
| Ala 298 | - | expression tag |
| Arg 372 | Leu 372 | engineered mutation |
| Ser 536 | Leu 536 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 117862.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1449.4 | |
| All* | Total formula weight | 119311.8 |
