3OP3

Crystal Structure of Cell Division Cycle 25C Protein Isoform A from Homo sapiens

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	M-phase inducer phosphatase 3	polymer	216	25407.9	1	UniProt (P30307) Pfam (PF00581)	Homo sapiens (human)	Dual specificity phosphatase Cdc25C
2	B, C, D, E (A)	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3	F (A)	water	water		18.0	44	Chemie (HOH)

Sequence modifications

A: 270 - 462 (UniProt: P30307)

PDB	External Database	Details
Met 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
Ser 254	-	expression tag
Ser 255	-	expression tag
Gly 256	-	expression tag
Val 257	-	expression tag
Asp 258	-	expression tag
Leu 259	-	expression tag
Gly 260	-	expression tag
Thr 261	-	expression tag
Glu 262	-	expression tag
Asn 263	-	expression tag
Leu 264	-	expression tag
Tyr 265	-	expression tag
Phe 266	-	expression tag
Gln 267	-	expression tag
Ser 268	-	expression tag
Met 269	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	25407.9
Non-Polymers*	Number of molecules	4
	Total formula weight	384.3
All*	Total formula weight	25792.1

*Water molecules are not included.