3OIL
Human Carbonic anhydrase II mutant A65S, N67Q (CA IX mimic) bound by 2-Ethylestradiol 3-O-sulfamate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 260 | 29319.1 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (human) | Carbonic anhydrase II, CA-II, Carbonate dehydratase II, Carbonic anhydrase C, CAC |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | (14beta,17alpha)-2-ethyl-17-hydroxyestra-1(10),2,4-trien-3-yl sulfamate | non-polymer | 379.5 | 1 | Chemie (VZ5) | |||
| 4 | D (A) | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence modifications
A: 1 - 261 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Ser 65 | Ala 65 | engineered mutation |
| Gln 67 | Asn 67 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29319.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 444.9 | |
| All* | Total formula weight | 29764.0 |
