3OHX

Molecular Basis for Complement Recognition and Inhibition Determined by Crystallographic Studies of the Staphylococcal Complement Inhibitor (SCIN) Bound to C3c and C3b

Replaces:  3NSA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	Complement C3	polymer	645	71393.3	2	UniProt (P01024) Pfam (PF17790) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) In PDB	Homo sapiens (human)
2	B, E	Complement C3	polymer	206	23621.2	2	UniProt (P01024) Pfam (PF00207) Pfam (PF21406) In PDB	Homo sapiens (human)
3	C, F	Complement C3	polymer	343	39537.4	2	UniProt (P01024) Pfam (PF01759) Pfam (PF21308) Pfam (PF07677) In PDB	Homo sapiens (human)
4	M, P	Staphylococcal complement inhibitor	polymer	88	10064.4	2	UniProt (Q931M7) Pfam (PF11546) In PDB	Staphylococcus aureus	SCIN
5	A, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

M, P: 1 - 85 (UniProt: Q931M7)

PDB	External Database	Details
Gly -2	-	expression tag
Thr -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	289232.7
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	289675.1

*Water molecules are not included.