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3OF9

Structural Basis for Irreversible Inhibition of Human Cathepsin L by a Diazomethylketone Inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cathepsin L1polymer22124320.81UniProt (P07711)
Pfam (PF00112)
Homo sapiens (human)Major excreted protein, MEP, Cathepsin L1 heavy chain, Cathepsin L1 light chain
2B
(A)
Nalpha-[(benzyloxy)carbonyl]-N-[(1S)-1-(4-tert-butoxybenzyl)-3-diazo-2-oxopropyl]-L-phenylalaninamidenon-polymer542.61BIRD (PRD_000784)
Chemie (I0X)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24320.8
Non-Polymers*Number of molecules1
Total formula weight542.6
All*Total formula weight24863.4
*Water molecules are not included.

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PDB entries from 2024-11-13

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