3OF8
Structural Basis for Reversible and Irreversible Inhibition of Human Cathepsin L by their Respective Dipeptidyl Glyoxal and Diazomethylketone Inhibitors
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cathepsin L1 | polymer | 221 | 24320.8 | 1 | UniProt (P07711) Pfam (PF00112) | Homo sapiens (human) | Major excreted protein, MEP, Cathepsin L1 heavy chain, Cathepsin L1 light chain |
| 2 | B (A) | Nalpha-[(benzyloxy)carbonyl]-N-[(2S)-1-(4-tert-butoxyphenyl)-4-hydroxy-3-oxobutan-2-yl]-L-phenylalaninamide | non-polymer | 532.6 | 1 | BIRD (PRD_000782) Chemie (I0Y) | |||
| 3 | C (A) | water | water | 18.0 | 47 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 24320.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 532.6 | |
| All* | Total formula weight | 24853.4 |
