3OF6

Human pre-T cell receptor crystal structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	T cell receptor beta chain	polymer	255	28607.6	3		Homo sapiens (human)
2	D, E, F (D, E, F)	Pre T-cell antigen receptor alpha	polymer	130	13387.9	3	UniProt (Q6ISU1) Pfam (PF15028)	Homo sapiens (human)	pre-T alpha chain, pT-alpha, pTa, pT-alpha-TCR
3	G, H, I, J (C, D, E, F)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
4	K, L, M, N, O... (A, B, C, D, E...)	water	water		18.0	109	Chemie (HOH)

Sequence modifications

D, E, F: 1 - 119 (UniProt: Q6ISU1)

PDB	External Database	Details
Gly -3	-	expression tag
Ala -2	-	expression tag
His -1	-	expression tag
Met 0	-	expression tag
Ser 120	-	expression tag
Gly 121	-	expression tag
Asp 122	-	expression tag
Asp 123	-	expression tag
Asp 124	-	expression tag
Asp 125	-	expression tag
Lys 126	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	125986.4
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	126871.2

*Water molecules are not included.