3ODW

Crystal Structure of the Linker-DH/PH domains of p115-RhoGEF

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Rho guanine nucleotide exchange factor 1	polymer	536	61079.4	2	UniProt (Q92888) Pfam (PF00621) Pfam (PF17838)	Homo sapiens (human)	115 kDa guanine nucleotide exchange factor, p115-RhoGEF, p115RhoGEF, Sub1.5

Sequence modifications

A, B: 240 - 766 (UniProt: Q92888)

PDB	External Database	Details
Gln 237	-	expression tag
Thr 238	-	expression tag
Ser 239	-	expression tag
His 767	-	expression tag
His 768	-	expression tag
His 769	-	expression tag
His 770	-	expression tag
His 771	-	expression tag
His 772	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	122158.7
All*	Total formula weight	122158.7

*Water molecules are not included.