3OB2
Crystal structure of c-Cbl TKB domain in complex with double phosphorylated EGFR peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 12-meric peptide from Epidermal growth factor receptor | polymer | 12 | 1576.4 | 1 | UniProt (P00533) | Homo sapiens | Receptor tyrosine-protein kinase erbB-1, Proto-oncogene c-ErbB-1 |
| 2 | B (B) | E3 ubiquitin-protein ligase CBL | polymer | 329 | 38192.1 | 1 | UniProt (P22681) Pfam (PF02262) Pfam (PF02761) Pfam (PF02762) | Homo sapiens (human) | Signal transduction protein CBL, Proto-oncogene c-Cbl, Casitas B-lineage lymphoma proto-oncogene, RING finger protein 55 |
| 3 | C, D (A, B) | water | water | 18.0 | 314 | Chemie (HOH) |
Sequence modifications
B: 25 - 351 (UniProt: P22681)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Ser 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 39768.5 | |
| All* | Total formula weight | 39768.5 |
