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3OAU

Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Non-Domain-Exchanged Forms, but only binds the HIV-1 Glycan Shield if Domain-Exchanged

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
Fab 2G12, heavy chainpolymer22523976.91Homo sapiens
2B
(L)
Fab 2G12, light chainpolymer21223130.81Homo sapiens
3C
(A)
alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranosebranched342.31In PDB
BIRD (PRD_900111)
GlyTouCan (G53402KW)
2alpha-alpha-mannobiose
4D, E
(H)
SULFATE IONnon-polymer96.12Chemie (SO4)
5F
(L)
GLYCEROLnon-polymer92.11Chemie (GOL)
6G, H
(H, L)
waterwater18.0195Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight47107.7
BranchedNumber of molecules1
Total formula weight342.3
Non-Polymers*Number of molecules3
Total formula weight284.2
All*Total formula weight47734.2
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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