3O9I
Crystal Structure of wild-type HIV-1 Protease in complex with af61
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 99 | 10815.8 | 2 | UniProt (Q90K99) Pfam (PF00077) UniProt (by SIFTS) (P03369) | Human immunodeficiency virus 1 (HIV-1) | |
| 2 | C, D, F, G (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) PubChem (1061) | |||
| 3 | E (A) | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl {(1S,2R)-3-[(1,3-benzothiazol-6-ylsulfonyl)(2-ethylbutyl)amino]-1-benzyl-2-hydroxypropyl}carbamate | non-polymer | 617.8 | 1 | Chemie (A61) PubChem (53308636) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: Q90K99)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21631.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 997.7 | |
| All* | Total formula weight | 22629.2 |
