3O8C

Visualizing ATP-dependent RNA Translocation by the NS3 Helicase from HCV

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, B)	HCV NS3 protease/helicase	polymer	666	70869.4	2	UniProt (Q99AU2) Pfam (PF02907) Pfam (PF07652) Pfam (PF22027)	Hepatitis C virus subtype 1b
2	B (C)	RNA (5'-R(P*UP*(5BU)P*UP*UP*UP*U)-3')	polymer	6	1870.9	1
3	D, F (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4	E, G (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	H, I, J (A, C, B)	water	water		18.0	796	Chemie (HOH)

Sequence modifications

A, B: 3 - 631 (UniProt: Q99AU2)

PDB	External Database	Details
Met -36	-	expression tag
Gly -35	-	expression tag
Ser -34	-	expression tag
Ser -33	-	expression tag
His -32	-	expression tag
His -31	-	expression tag
His -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
Ser -26	-	expression tag
Ser -25	-	expression tag
Gly -24	-	expression tag
Leu -23	-	expression tag
Val -22	-	expression tag
Pro -21	-	expression tag
Arg -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
Met -16	-	expression tag
Gly -15	-	expression tag
Ser -14	-	expression tag
Val -13	-	expression tag
Val -12	-	expression tag
Ile -11	-	expression tag
Val -10	-	expression tag
Gly -9	-	expression tag
Arg -8	-	expression tag
Ile -7	-	expression tag
Ile -6	-	expression tag
Leu -5	-	expression tag
Ser -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	143609.7
Non-Polymers*	Number of molecules	4
	Total formula weight	322.9
All*	Total formula weight	143932.7

*Water molecules are not included.