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3O7W

The Crystal Structure of Human Leucine Carboxyl Methyltransferase 1

Replaces:  3MNT
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Leucine carboxyl methyltransferase 1polymer29433910.91UniProt (Q9UIC8)
Pfam (PF04072)
Homo sapiens (human)Protein-leucine O-methyltransferase
2B
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
3C
(A)
S-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
4D
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
5E
(A)
waterwater18.0138Chemie (HOH)
Sequence modifications
A: 23 - 334 (UniProt: Q9UIC8)
PDBExternal DatabaseDetails
Gly 17-expression tag
Ala 18-expression tag
Met 19-expression tag
Asp 20-expression tag
Glu 21-expression tag
Asn 22-expression tag
Glu 233-linker
Gly 234-linker
-Met 233deletion
-Gly 234deletion
-Asp 235deletion
-Arg 236deletion
-Phe 237deletion
-Gly 238deletion
-Gln 239deletion
-Ile 240deletion
-Met 241deletion
-Ile 242deletion
-Asn 244deletion
-Leu 245deletion
-Arg 246deletion
-Arg 247deletion
-Arg 248deletion
-Gln 249deletion
-Cys 250deletion
-Asp 251deletion
-Leu 252deletion
-Ala 253deletion
-Val 255deletion
-Glu 256deletion
-Thr 257deletion
-Cys 258deletion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight33910.9
Non-Polymers*Number of molecules3
Total formula weight513.5
All*Total formula weight34424.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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