3O77
The structure of Ca2+ Sensor (Case-16)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Myosin light chain kinase, smooth muscle,Green fluorescent protein,Green fluorescent protein,Calmodulin-1 | polymer | 417 | 46477.9 | 1 | UniProt (P11799) UniProt (P42212) UniProt (P0DP23) Pfam (PF01353) Pfam (PF13499) | Gallus gallus (Chicken) | MLCK,Telokin |
| 2 | B, C (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | D, E (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | G (A) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A: 5 - 24 (UniProt: P11799)
A: 25 - 116 (UniProt: P42212)
A: 126 - 270 (UniProt: P42212)
A: 271 - 417 (UniProt: P0DP23)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Pro 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Ser 4 | - | expression tag |
| Ser 5 | Ala 1730 | engineered mutation |
| Asn 10 | Gln 1735 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Leu 25 | Ser 147 | engineered mutation |
| Glu 26 | His 148 | engineered mutation |
| Ala 41 | Val 163 | engineered mutation |
| Val 49 | Ile 171 | engineered mutation |
| Phe 81 | Thr 203 | engineered mutation |
| Val 84 | Ala 206 | engineered mutation |
| Leu 109 | His 231 | engineered mutation |
| Asn 116 | Lys 238 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Val 117 | - | linker |
| Asp 118 | - | linker |
| Gly 119 | - | linker |
| Gly 120 | - | linker |
| Ser 121 | - | linker |
| Gly 122 | - | linker |
| Gly 123 | - | linker |
| Thr 124 | - | linker |
| Gly 125 | - | linker |
| Leu 170 | Phe 46 | engineered mutation |
| Leu 188 | Phe 64 | engineered mutation |
| Cr2 190 | Ser 65 | chromophore |
| Cr2 190 | Tyr 66 | chromophore |
| Cr2 190 | Gly 67 | chromophore |
| Leu 192 | Val 68 | engineered mutation |
| Lys 193 | Gln 69 | engineered mutation |
| Ala 196 | Ser 72 | see sequence details |
| Gly 253 | Asp 129 | engineered mutation |
| Ser 269 | Tyr 145 | engineered mutation |
| Arg 270 | Asn 146 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46477.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 307.7 | |
| All* | Total formula weight | 46785.6 |
