3O2Y
Structure-function analysis of human L-Prostaglandin D Synthase bound with fatty acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Prostaglandin-H2 D-isomerase | polymer | 162 | 18089.3 | 2 | UniProt (P41222) Pfam (PF00061) | Homo sapiens (human) | Lipocalin-type prostaglandin-D synthase, Glutathione-independent PGD synthase, Prostaglandin-D2 synthase, PGD2 synthase, PGDS2, PGDS, Beta-trace protein, Cerebrin-28 |
| 2 | C, E (A, B) | OLEIC ACID | non-polymer | 282.5 | 2 | Chemie (OLA) | |||
| 3 | D, F (A, B) | PALMITIC ACID | non-polymer | 256.4 | 2 | Chemie (PLM) | |||
| 4 | G (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 155 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 190 (UniProt: P41222)
| PDB | External Database | Details |
|---|---|---|
| Ala 65 | Cys 65 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36178.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1169.9 | |
| All* | Total formula weight | 37348.4 |
