3O2S

Crystal structure of the human symplekin-Ssu72 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Symplekin	polymer	351	39647.0	1	UniProt (Q92797) Pfam (PF11935)	Homo sapiens (human)
2	B (B)	RNA polymerase II subunit A C-terminal domain phosphatase SSU72	polymer	214	24774.9	1	UniProt (Q9NP77) Pfam (PF04722)	Homo sapiens (human)	CTD phosphatase SSU72
3	C (B)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
4	D, E (A, B)	water	water		18.0	76	Chemie (HOH)

Sequence modifications

A: 30 - 360 (UniProt: Q92797)

PDB	External Database	Details
Met 10	-	expression tag
Gly 11	-	expression tag
Ser 12	-	expression tag
Ser 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
Ser 20	-	expression tag
Ser 21	-	expression tag
Gly 22	-	expression tag
Leu 23	-	expression tag
Val 24	-	expression tag
Pro 25	-	expression tag
Arg 26	-	expression tag
Gly 27	-	expression tag
Ser 28	-	expression tag
His 29	-	expression tag

B: 1 - 194 (UniProt: Q9NP77)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	64421.8
Non-Polymers*	Number of molecules	1
	Total formula weight	95.0
All*	Total formula weight	64516.8

*Water molecules are not included.