3O1G
Cathepsin K covalently bound to a 2-cyano pyrimidine inhibitor with a benzyl P3 group.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cathepsin K | polymer | 215 | 23523.5 | 1 | UniProt (P43235) Pfam (PF00112) | Homo sapiens (human) | Cathepsin O, Cathepsin X, Cathepsin O2 |
| 2 | B, C (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | D (A) | N-benzyl-3-(2-cyano-6-propylpyrimidin-4-yl)-N-[2-(dimethylamino)ethyl]-5-(trifluoromethyl)benzamide | non-polymer | 495.5 | 1 | Chemie (O75) | |||
| 4 | E (A) | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23523.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 687.7 | |
| All* | Total formula weight | 24211.1 |
