3NZJ
Crystal structure of yeast 20S proteasome in complex with ligand 2a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, O (A, O) | Proteasome component Y7 | polymer | 250 | 27191.8 | 2 | UniProt (P23639) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit Y7, Multicatalytic endopeptidase complex subunit Y7, Proteinase YSCE subunit 7 |
| 2 | B, P (B, P) | Proteasome component Y13 | polymer | 258 | 28748.2 | 2 | UniProt (P23638) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit Y13, Multicatalytic endopeptidase complex subunit Y13, Proteinase YSCE subunit 13 |
| 3 | C, Q (C, Q) | Proteasome component PRE6 | polymer | 254 | 28478.1 | 2 | UniProt (P40303) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PRE6, Multicatalytic endopeptidase complex subunit PRE6, Proteinase YSCE subunit PRE6 |
| 4 | D, R (D, R) | Proteasome component PUP2 | polymer | 260 | 28649.1 | 2 | UniProt (P32379) Pfam (PF00227) Pfam (PF10584) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PUP2, Multicatalytic endopeptidase complex subunit PUP2, Proteinase YSCE subunit PUP2 |
| 5 | E, S (E, S) | Proteasome component PRE5 | polymer | 234 | 25634.0 | 2 | UniProt (P40302) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PRE5, Multicatalytic endopeptidase complex subunit PRE5, Proteinase YSCE subunit PRE5 |
| 6 | F, T (F, T) | Proteasome component C1 | polymer | 288 | 31575.1 | 2 | UniProt (P21242) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit C1, Multicatalytic endopeptidase complex subunit C1, Proteinase YSCE subunit 1 |
| 7 | G, U (G, U) | Proteasome component C7-alpha | polymer | 252 | 28033.8 | 2 | UniProt (P21243) Pfam (PF10584) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit C7-alpha, Multicatalytic endopeptidase complex C7, Proteasome component Y8, Proteinase YSCE subunit 7, SCL1 suppressor protein |
| 8 | H, V (H, V) | Proteasome component PUP1 | polymer | 261 | 28299.9 | 2 | UniProt (P25043) Pfam (PF00227) Pfam (PF12465) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PUP1, Multicatalytic endopeptidase complex subunit PUP1, Proteinase YSCE subunit PUP1 |
| 9 | I, W (I, W) | Proteasome component PUP3 | polymer | 205 | 22627.8 | 2 | UniProt (P25451) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PUP3, Multicatalytic endopeptidase complex subunit PUP3 |
| 10 | J, X (J, X) | Proteasome component C11 | polymer | 198 | 22545.7 | 2 | UniProt (P22141) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit C11, Multicatalytic endopeptidase complex subunit C11, Proteinase YSCE subunit 11 |
| 11 | K, Y (K, Y) | Proteasome component PRE2 | polymer | 287 | 31670.5 | 2 | UniProt (P30656) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PRE2, Multicatalytic endopeptidase complex subunit PRE2, Proteinase YSCE subunit PRE2 |
| 12 | L, Z (L, Z) | Proteasome component C5 | polymer | 241 | 26905.1 | 2 | UniProt (P23724) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Multicatalytic endopeptidase complex subunit C5 |
| 13 | AA, M (M, 1) | Proteasome component PRE4 | polymer | 266 | 29471.3 | 2 | UniProt (P30657) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PRE4, Multicatalytic endopeptidase complex subunit PRE4, Proteinase YSCE subunit PRE4 |
| 14 | BA, N (N, 2) | Proteasome component PRE3 | polymer | 215 | 23573.6 | 2 | UniProt (P38624) Pfam (PF00227) | Saccharomyces cerevisiae (brewer's yeast lager beer yeast yeast) | Macropain subunit PRE3, Multicatalytic endopeptidase complex subunit PRE3, Proteinase YSCE subunit PRE3 |
| 15 | CA, DA (3, 4) | TMC-95A mimic ligand 2a | polymer | 5 | 733.9 | 2 | BIRD (PRD_001103) | ||
| 16 | EA, FA (K, Y) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 17 | AB, BB, CB, DB, EB... (U, V, W, X, Y...) | water | water | 18.0 | 1336 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 768275.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 390.5 | |
| All* | Total formula weight | 768666.3 |
