3NY4
Crystal Structure of BlaC-K73A bound with Cefamandole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 265 | 28214.6 | 1 | UniProt (P0C5C1) Pfam (PF13354) UniProt (by SIFTS) (P9WKD3) | Mycobacterium tuberculosis | Penicillinase |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) PubChem (1061) | |||
| 3 | C, D, E, F, G (A) | (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | non-polymer | 462.5 | 5 | Chemie (SMX) PubChem (34780) PubChem (36831) PubChem (22794636) PubChem (22814242) PubChem (25271120) PubChem (36688107) PubChem (36688109) PubChem (40469431) PubChem (456255) PubChem (51397052) PubChem (58650820) PubChem (68149539) PubChem (70376443) PubChem (2614) PubChem (6604545) PubChem (90437946) PubChem (12799152) PubChem (12853014) PubChem (118410309) PubChem (151347697) | |||
| 4 | H (A) | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 43 - 307 (UniProt: P0C5C1)
| PDB | External Database | Details |
|---|---|---|
| Ala 87 | Lys 87 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28214.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2407.5 | |
| All* | Total formula weight | 30622.1 |
