3NY4
Crystal Structure of BlaC-K73A bound with Cefamandole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase | polymer | 265 | 28214.6 | 1 | UniProt (P0C5C1) Pfam (PF00144) Pfam (PF13354) UniProt (by SIFTS) (P9WKD3) | Mycobacterium tuberculosis | Penicillinase |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C, D, E, F, G (A) | (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | non-polymer | 462.5 | 5 | Chemie (SMX) | |||
| 4 | H (A) | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 43 - 307 (UniProt: P0C5C1)
| PDB | External Database | Details |
|---|---|---|
| Ala 87 | Lys 87 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28214.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2407.5 | |
| All* | Total formula weight | 30622.1 |
