3NY4
Crystal Structure of BlaC-K73A bound with Cefamandole
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Beta-lactamase | polymer | 265 | 28214.6 | 1 | UniProt (P0C5C1) Pfam (PF00144) Pfam (PF13354) UniProt (by SIFTS) (P9WKD3) In PDB | Mycobacterium tuberculosis | Penicillinase |
2 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
3 | A | (6R,7R)-7-{[(2R)-2-hydroxy-2-phenylacetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | non-polymer | 462.5 | 5 | Chemie (SMX) | |||
4 | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 43 - 307 (UniProt: P0C5C1)
PDB | External Database | Details |
---|---|---|
Ala 87 | Lys 87 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 28214.6 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 2407.5 | |
All* | Total formula weight | 30622.1 |