3NXP
Crystal structure of human prethrombin-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Prethrombin-1 | polymer | 424 | 47836.7 | 1 | UniProt (P00734) Pfam (PF00051) Pfam (PF09396) Pfam (PF00089) | Homo sapiens (human) | Coagulation factor II |
| 2 | B (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 3 | C, D (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 4 | E, F (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | G (A) | water | water | 18.0 | 197 | Chemie (HOH) |
Sequence modifications
A: 156 - 647 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Ala 271 | Arg 314 | engineered mutation |
| Ala 284 | Arg 327 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47836.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 649.7 | |
| All* | Total formula weight | 48486.4 |
