3NT1
High resolution structure of naproxen:COX-2 complex.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Prostaglandin-endoperoxide synthase 2 | polymer | 587 | 67332.7 | 2 | UniProt (Q543K3) Pfam (PF00008) Pfam (PF03098) UniProt (by SIFTS) (Q05769) | Mus musculus (mouse) | |
| 2 | C, D (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | E, F, M, Q (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 4 | G, J, K, O (A, B) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 4 | Chemie (BOG) | |||
| 5 | H, N (A, B) | (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid | non-polymer | 230.3 | 2 | Chemie (NPS) | |||
| 6 | I, P (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 7 | L, R (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 8 | S, T (A, B) | water | water | 18.0 | 1051 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 134665.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 3818.7 | |
| All* | Total formula weight | 139332.9 |
