3NKX
Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 14-3-3 protein zeta/delta | polymer | 245 | 27777.1 | 2 | UniProt (P63104) Pfam (PF00244) | Homo sapiens (human) | Protein kinase C inhibitor protein 1, KCIP-1 |
| 2 | C, D (P, Q) | Peptide of RAF proto-oncogene serine/threonine-protein kinase | polymer | 10 | 1208.2 | 2 | UniProt (P04049) | Proto-oncogene c-RAF, cRaf, Raf-1 | |
| 3 | E (A) | PROPANOIC ACID | non-polymer | 74.1 | 1 | Chemie (PPI) | |||
| 4 | F, G, H, I (A, B, P, Q) | water | water | 18.0 | 183 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57970.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 74.1 | |
| All* | Total formula weight | 58044.6 |
