3NJ4
Fluoro-neplanocin A in Human S-Adenosylhomocysteine Hydrolase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Adenosylhomocysteinase | polymer | 435 | 48055.2 | 4 | UniProt (P23526) Pfam (PF05221) Pfam (PF00670) | Homo sapiens (human) | AdoHcyase, S-adenosyl-L-homocysteine hydrolase |
| 2 | E, G, I, K (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, H, J, L (A, B, C, D) | (4S,5S)-4-(6-amino-9H-purin-9-yl)-3-fluoro-5-hydroxy-2-(hydroxymethyl)cyclopent-2-en-1-one | non-polymer | 279.2 | 4 | Chemie (AFX) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 258 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 432 (UniProt: P23526)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 192220.9 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3770.6 | |
| All* | Total formula weight | 195991.5 |
